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Analysis of Sumatriptan and Eletriptan By Capaillary Electrophoresis | Khemthong | งดใช้ระบบ 3-31 กค 66 Burapha Science Journal

Analysis of Sumatriptan and Eletriptan By Capaillary Electrophoresis

Napat Khemthong

Abstract


Analysis of sumatriptan and eletriptan by capillary electrophoresis with UV detection was studied. Under the optimized conditions, analytes could be completely separated within 2 min. Limits of detections and limits of quantitations of sumatriptan and eletriptan were 0.30 and 0.60 mg/L, and 0.90 and 1.80 mg/L, respectively. Linearity of sumatriptan (0.90-50.00 mg/L) with R2 = 0.9993 and eletriptan (1.80-50.00 mg/L) with R2 = 0.9994 were obtained. Relative standard deviations of migration times of sumatriptan and eletriptan were less than 0.77%. Relative standard deviations of peak areas of sumatriptan and eletriptan were less than 6.46%.

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