Free Radical Scavenging and Ferrous Chelating Activities of Thai Marine Sponge Extracts

Puntip Wisespongpand; Komson Hongpadharakiree; Atthavut Kanthawong

Free Radical Scavenging and Ferrous Chelating Activities of Thai Marine Sponge Extracts

Puntip Wisespongpand, Komson Hongpadharakiree, Atthavut Kanthawong

Abstract

Twenty-three samples of Thai marine sponges were evaluated for antioxidant activities by comparing the effect of three solvents on the antioxidant activities. Almost of methanolic extracts displayed high DPPH radical scavenging and ferrous chelating activity while methanolic and acetone extracts displayed high ABTS radical scavenging activity. Dichloromethane extracts almost displayed low antioxidant activities. The most significant ABTS and DPPH scavenging activity were determined for the methanolic extract from Hyrtios sp.1 at IC₅₀ value of 77.14 and 228.9 µg/ml, respectively. The dichloromethane extract from Stylissa sp. had the most significant ferrous chelating activity at IC₅₀ value of 159.4 µg/ml. Hyrtios sp.1 had the highest phenol content at the value of 124.27±3.73 mgGAE/g of extract which supposed to perform its radical scavenging activities.

Keywords : sponge, free radical scavenging, DPPH, ABTS, ferrous chelating

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References

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